1 Associate Professor, Department of RSBK, Rajeev Institute of Ayurvedic Medical Science & Research Centre, Hassan, Karnataka, India.
2 Professor & HOD, Department of RSBK, Alva’s Ayurveda Mecical College, Moodbidri, Karnataka, India
3 Professor & HOD, Department of RSBK, Rajeev Institute of Ayurvedic Medical Science & Research Centre, Hassan, Karnataka, India.
World Journal of Biology Pharmacy and Health Sciences, 2025, 21(02), 176-182
Article DOI: 10.30574/wjbphs.2025.21.2.0120
Received on 21 December 2024; revised on 31 January 2025; accepted on 02 February 2025
Ancient acharyas of Ayurveda had an excellent knowledge of the properties and action of the single drugs. Through their deep insight they formulated enumerable yogas by the combination of these single drugs. Various research studies have proved the efficacy of these formulations. This article attempts to analyze the action of one such formulation Saindhavadya Ghruta, indicated for Apasmara and Graha Doshas in Yogaratnakara. In an experimental study undertaken, Saindhavadya Ghruta showed good anti-convulsant activity. It proves to be an excellent drug designing by the author. Previous studies indicated that all the ingredients of the preparation are independently having anti-convulsant action. Even the drugs used for murcchana have been studied to have anti-convulsant activity individually. Hence, it proves the synergistic action of the drugs combined in the formulation judiciously to pronounce the total action of the yoga.
Saindhavadya Ghruta; Anti-convulsant activity; Apasmara; PTZ Kindling in mice; Blood brain barrier
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Shilpa S. N, Krishnamurthy M. S and Ajay Kumar K. A. Analyses of action of Saindhavadya ghruta W.S.R. to its anti-convulsant activity. World Journal of Biology Pharmacy and Health Sciences, 2025, 21(02), 176-182. Article DOI: https://doi.org/10.30574/wjbphs.2025.21.2.0120.
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